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Caroline Gachema

Caroline Gachema

Biomedical Scientist  ·  Bioinformatician  ·  Global Health Researcher

📍 Nairobi, Kenya

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1,832
Samples Analysed
5+
Computational Projects
3
Research Papers
BSL-3
Wet Lab Certified

Featured Work

A selection of projects across research, computation, and policy

Translational Oncology
Psychedelic Neuroplasticity and the Neurotrophic Architecture of Pancreatic Cancer
Cross-disciplinary analysis connecting psilocybin neuroplasticity (TrkB) with perineural invasion in pancreatic cancer (TrkA) — with TCGA-PAAD validation across 182 tumour samples.
R GSEA Survival Analysis TCGA
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Machine Learning
Machine Learning Framework for Alzheimer's Detection
Random Forest classifier trained on ADNI dataset features achieving 90.7% cross-validation accuracy in distinguishing Alzheimer's disease from cognitively normal controls.
Python scikit-learn Random Forest ADNI
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Health Policy
Why the HIV Stem Cell Cure Is Nearly Irrelevant for Sub-Saharan Africa
Population genetics and structural analysis of HIV cure research equity, with WHO-directed recommendations on equitable trial design.
Policy Analysis AfricArXiv WHO
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About Me

Caroline Gachema

My work sits at the intersection of molecular biology, bioinformatics, and global health policy — combining hands-on lab experience with computational analysis to generate rigorous, reproducible results. I’m drawn to the questions that sit on the edge of what we know, and how data can be made to serve the people it describes.

Skills & Tools

Bioinformatics & Genomics

R Python DESeq2 clusterProfiler GSEA Survival Analysis ggplot2 TCGA Data UCSC Xena

Machine Learning & Data Science

Random Forest scikit-learn Cross-validation Feature Engineering Data Wrangling

Wet Lab & Clinical

GeneXpert MTB/RIF BSL-3 Biosafety Phlebotomy ELISA GC-MS PCR Cell Culture

Research & Communication

Scientific Writing Policy Analysis GitHub Quarto

Let's connect

Open to research collaborations, internships, and opportunities in computational biology and global health

✉ gachemacarol@gmail.com GitHub LinkedIn
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